Periaquaductal grey pain modulation pathway

The periaquaductal grey pathway is the descending pathway that helps modulate pain. There are so many double/triple/quadruple negatives in this pathway it makes the head spin. Who knew that the activation of the inhibitory interneuron would inhibit the other inhibitory interneuron, releasing inhibition of another neuron only to inhibit pain?

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  1. Pingback: Spilt Martini » Periaquaductal Grey Pain Modulation Pathway

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